Cheat SheetBSPH

Surgical Pharmacology Quick Reference

A condensed chart of drug classes commonly used in the OR, their purpose, and key safety considerations for the sterile field.

Medications on the Sterile Field

The scrub person is responsible for identifying, labeling, and managing all medications and solutions on the sterile field, and for verbally confirming each with the circulator before use. This section is a fast-recall summary of the drug classes most tested on the CST exam.

Local Anesthetics

DrugOnset/DurationNote
LidocaineFast onset, short-intermediate durationCommon for local infiltration and nerve blocks; also available with epinephrine
Bupivacaine (Marcaine)Slower onset, long durationUsed for prolonged postoperative pain control
RopivacaineIntermediate onset, long durationSimilar to bupivacaine with a reduced cardiotoxicity profile

Hemostatic and Vasoconstrictive Agents

DrugPurpose
EpinephrineVasoconstriction to reduce bleeding and prolong local anesthetic effect; avoided in end-arterial tissue
Topical thrombinConverts fibrinogen to fibrin at the bleeding site
Tranexamic acid (TXA)Antifibrinolytic used to reduce blood loss in select procedures

Irrigation Solutions

SolutionUse
Normal saline (0.9% NaCl)General wound and cavity irrigation
Sterile waterUsed in some oncologic cases for its cytolytic effect on residual tumor cells
Antibiotic irrigationDiluted antibiotic solution used per surgeon order to reduce bacterial load
Glycine or sorbitol solutionNon-electrolyte irrigant for monopolar resectoscope procedures (e.g., TURP) to avoid electrical conduction

Contrast and Diagnostic Agents

AgentUse
Iodinated contrast mediaIntraoperative cholangiography, angiography; screen for iodine/shellfish allergy history
Methylene blue / indigo carmineIdentifying ureters, fistula tracts, or confirming anastomotic integrity

Antibiotics

Prophylactic IV antibiotics are typically administered by anesthesia within 60 minutes before incision (per Surgical Care Improvement Project/SSI prevention guidelines) to achieve adequate tissue levels at the time of incision. Antibiotic irrigation may also be used directly in the wound per surgeon preference.

Medication Safety on the Field

  • All medications and solutions are labeled immediately upon receipt onto the sterile field, including name, strength/concentration, and time if applicable.
  • Verbal confirmation ("read-back") between scrub and circulator is completed for every medication passed to the field.
  • Look-alike containers (saline vs. local anesthetic vs. contrast) are a leading cause of OR medication errors - always verify visually and verbally.
  • Unlabeled medications/solutions on the sterile field must be discarded - never assumed or guessed.

Key Exam Points

  • Know which agents are avoided in end-arterial anatomy (epinephrine) and why.
  • Understand why nonconductive irrigants (glycine, sorbitol) are required for monopolar resectoscope procedures.
  • Recognize signs of local anesthetic systemic toxicity (LAST) as a rare but serious complication and the surgical tech's role in staying alert to changes reported by anesthesia.

This content is for educational purposes only. SurgicalTechPrep is independently developed and is not affiliated with, endorsed by, or sponsored by NBSTSA, AST, or any official certification body. All clinical information should be verified with current standards of practice.

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